Publications

Pubmed  ||  Google Scholar  ||  Faculty of 1000

SRF transcriptionally regulates the oligodendrocyte cytoskeleton during CNS myelination [Preprint]
Tal Iram, Miguel A. Garcia, Jérémy Amand, Achint Kaur, Manasi Iyer, Mable Lam, Nicolas Ambiel, Andreas Keller, Tony Wyss-Coray, Fabian Kern, J. Bradley Zuchero
bioRxiv 2022.09.21.508765; doi: https://doi.org/10.1101/2022.09.21.508765

CNS myelination requires VAMP2/3-mediated membrane expansion in oligodendrocytes.
Lam M, Takeo K, Almeida RG, Cooper MH, Wu K, Iyer M, Kantarci H, Zuchero JB. Nat Commun. 2022 Sep 23;13(1):5583. doi: 10.1038/s41467-022-33200-4. PMID: 36151203

Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17.
Iram T, Kern F, Kaur A, Myneni S, Morningstar AR, Shin H, Garcia MA, Yerra L, Palovics R, Yang AC, Hahn O, Lu N, Shuken SR, Haney MS, Lehallier B, Iyer M, Luo J, Zetterberg H, Keller A, Zuchero JB, Wyss-Coray T. Nature. 2022 May;605(7910):509-515. doi: 10.1038/s41586-022-04722-0. Epub 2022 May 11. PMID: 35545674

Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM.
Lanz TV, Brewer RC, Ho PP, Moon JS, Jude KM, Fernandez D, Fernandes RA, Gomez AM, Nadj GS, Bartley CM, Schubert RD, Hawes IA, Vazquez SE, Iyer M, Zuchero JB, Teegen B, Dunn JE, Lock CB, Kipp LB, Cotham VC, Ueberheide BM, Aftab BT, Anderson MS, DeRisi JL, Wilson MR, Bashford-Rogers RJM, Platten M, Garcia KC, Steinman L, Robinson WH. Nature. 2022 Mar;603(7900):321-327. doi: 10.1038/s41586-022-04432-7. Epub 2022 Jan 24. PMID: 35073561

Modeling myelin: A toolkit for exploring myelin's mysteries in vitro.
Cooper MH, Zuchero JB. Dev Cell. 2021 May 3;56(9):1215-1217. doi: 10.1016/j.devcel.2021.04.015. PMID: 33945781

Label-free optical detection of bioelectric potentials using electrochromic thin films.
Alfonso FS, Zhou Y, Liu E, McGuire AF, Yang Y, Kantarci H, Li D, Copenhaver E, Zuchero JB, Müller H, Cui B. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):17260-17268. doi: 10.1073/pnas.2002352117. Epub 2020 Jul 6. PMID: 3263200

How Support of Early Career Researchers Can Reset Science in the Post-COVID19 World.
Gibson EM, Bennett FC, Gillespie SM, Güler AD, Gutmann DH, Halpern CH, Kucenas SC, Kushida CA, Lemieux M, Liddelow S, Macauley SL, Li Q, Quinn MA, Roberts LW, Saligrama N, Taylor KR, Venkatesh HS, Yalçın B, Zuchero JB. Cell. 2020 Jun 25;181(7):1445-1449. doi: 10.1016/j.cell.2020.05.045. PMID: 32533917

Anchors Away: Glia-Neuron Adhesion Regulates Myelin Targeting and Growth.
Garcia MA, Zuchero JB. Developmental Cell. 2019 51:659-661. doi: 10.1016/j.devcel.2019.11.018. PMID: 31951538

A Tribute to Ben Barres: Remembrances from Barres Lab Members
Eroglu C, Emery B, Stevens B, Daneman R, Allen NJ, Ullian EM, Zhang Y, Zuchero JB, Foo LC, Agalliu D, Bennett M. Developmental Cell. 2018 44:4415-419.

Schwann cells use TAM receptor-mediated phagocytosis in addition to autophagy to clear myelin in a mouse model of nerve injury.
Brosius Lutz A, Chung WS, Sloan SA, Carson GA, Zhou L, Lovelett E, Posada S, Zuchero JB, Barres BA. Proc Natl Acad Sci USA. 2017 Sep 19;114(38):E8072-E8080.
PMID: 28874532

DeActs: genetically encoded tools for perturbing the actin cytoskeleton in single cells.
Harterink M, da Silva ME, Will L, Turan J, Ibrahim A, Lang AE, van Battum EY, Pasterkamp RJ, Kapitein LC, Kudryashov D, Barres BA, Hoogenraad CC, Zuchero JB. Nature Methods. 2017 May;14(5):479-482.
PMID: 28394337      DeActs plasmids available at addgene: LINK

Glia in mammalian development and disease.
Zuchero JB, Barres BA. Development. 2015 Nov 15;142(22):3805-9.
PMID: 26577203.

CNS myelin wrapping is driven by actin disassembly.
Zuchero JB, Fu MM, Sloan SA, Ibrahim A, Olson A, Zaremba A, Dugas JC, Wienbar S, Caprariello AV, Kantor C, Leonoudakis D, Lariosa-Willingham K, Kronenberg G, Gertz K, Soderling SH, Miller RH, Barres BA. Developmental Cell. 2015 Jul 27;34(2):152-67.
PMID: 26166300

Type IV collagen is an activating ligand for the adhesion G protein-coupled receptor GPR126.
Paavola KJ, Sidik H, Zuchero JB, Eckart M, Talbot WS. Science Signaling. 2014 Aug 12;7(338):ra76.
PMID: 25118328.

Purification and culture of dorsal root ganglion neurons.
Zuchero JB. Cold Spring Harb Protoc. 2014 Aug 1;2014(8):813-4.
PMID: 25086024.

Purification of dorsal root ganglion neurons from rat by immunopanning.
Zuchero JB. Cold Spring Harb Protoc. 2014 Aug 1;2014(8):826-38.
PMID: 25086011.

Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain.
Gibson EM, Purger D, Mount CW, Goldstein AK, Lin GL, Wood LS, Inema I, Miller SE, Bieri G, Zuchero JB, Barres BA, Woo PJ, Vogel H, Monje M. Science. 2014 May 2;344(6183):1252304.
PMID: 24727982.

Cytoplasmic actin: purification and single molecule assembly assays.
Hansen SD, Zuchero JB, Mullins RD. Methods Mol Biol. 2013;1046:145-70.
PMID: 23868587.

Intrinsic and extrinsic control of oligodendrocyte development.
Zuchero JB, Barres BA. Curr Opin Neurobiol. 2013 Dec;23(6):914-20.
PMID: 23831087.

Generation of oligodendroglial cells by direct lineage conversion.
Yang N, Zuchero JB, Ahlenius H, Marro S, Ng YH, Vierbuchen T, Hawkins JS, Geissler R, Barres BA, Wernig M. Nature Biotechnology. 2013 May;31(5):434-9.
PMID: 23584610.

Actin binding to WH2 domains regulates nuclear import of the multifunctional actin regulator JMY.
Zuchero JB, Belin B, Mullins RD. Mol Biol Cell. 2012 Mar;23(5):853-63.
PMID: 22262458.

Between the sheets: a molecular sieve makes myelin membranes.
Zuchero JB, Barres BA. Developmental Cell. 2011 Sep 13;21(3):385-6.
PMID: 21920305

Hts/Adducin controls synaptic elaboration and elimination.
Pielage J, Bulat V, Zuchero JB, Fetter RD, Davis GW. Neuron. 2011 Mar 24;69(6):1114-31.
PMID: 21435557.

p53-cofactor JMY is a multifunctional actin nucleation factor.
Zuchero JB, Coutts AS, Quinlan ME, Thangue NB, Mullins RD. Nature Cell Biology. 2009 Apr;11(4):451-9.
PMID: 19287377.

In vitro actin assembly assays and purification from Acanthamoeba.
Zuchero JB. Methods Mol Biol. 2007;370:213-26.
PMID: 17416997.