Publications

Pubmed  ||  Google Scholar   ||  (Zuchero lab members underlined below)

pHusion - a robust and versatile toolset for automated detection and analysis of exocytosis.

O'Shaughnessy EC, Lam M, Ryken SE, Wiesner T, Lukasik K, Zuchero JB, Leterrier C, Adalsteinsson D, Gupton SL. J Cell Sci. 2024 Oct 15;137(20):jcs261828. doi: 10.1242/jcs.261828. Epub 2024 Jun 7. PMID: 38690758
Schwann cell-secreted PGE2 promotes sensory neuron excitability during development.

Kantarci H, Elvira PD, Thottumkara AP, O'Connell EM, Iyer M, Donovan LJ, Dugan MQ, Ambiel N, Granados A, Zeng H, Saw NL, Brosius Lutz A, Sloan SA, Gray EE, Tran KV, Vichare A, Yeh AK, Münch AE, Huber M, Agrawal A, Morri M, Zhong H, Shamloo M, Anderson TA, Tawfik VL, Du Bois J, Zuchero JB. Cell. 2024 Aug 22;187(17):4690-4712.e30. doi: 10.1016/j.cell.2024.07.033. Epub 2024 Aug 13. PMID: 39142281
Translating Molecular Approaches to Oligodendrocyte-Mediated Neurological Circuit Modulation.

Song J, Saglam A, Zuchero JB, Buch VP. Brain Sci. 2024 Jun 27;14(7):648. doi: 10.3390/brainsci14070648. PMID: 39061389
Optical Control of G-Actin with a Photoswitchable Latrunculin.

Vepřek NA, Cooper MH, Laprell L, Yang EJ, Folkerts S, Bao R, Boczkowska M, Palmer NJ, Dominguez R, Oertner TG, Pon LA, Zuchero JB, Trauner DH. J Am Chem Soc. 2024 Apr 3;146(13):8895-8903. doi: 10.1021/jacs.3c10776. Epub 2024 Mar 21. PMID: 38511265
SRF transcriptionally regulates the oligodendrocyte cytoskeleton during CNS myelination.

Iram T, Garcia MA, Amand J, Kaur A, Atkins M, Iyer M, Lam M, Ambiel N, Jorgens DM, Keller A, Wyss-Coray T, Kern F, Zuchero JB. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2307250121. doi: 10.1073/pnas.2307250121. Epub 2024 Mar 14. PMID: 38483990

Oligodendrocyte calcium signaling promotes actin-dependent myelin sheath extension
Iyer M, Kantarci H, Cooper MH, Ambiel N, Novak SW, Andrade LR, Lam M, Jones G, Münch AE, Yu X, Khakh BS, Manor U, Zuchero JB. Nat Commun. 2024 Jan 4;15(1):265. doi: 10.1038/s41467-023-44238-3. PMID: 38177161

Focused ultrasound-induced inhibition of peripheral nerve fibers in an animal model of acute pain.

Anderson TA, Pacharinsak C, Vilches-Moure J, Kantarci H, Zuchero JB, Butts-Pauly K, Yeomans D. Reg Anesth Pain Med. 2023 Sep;48(9):462-470. doi: 10.1136/rapm-2022-104060. Epub 2023 Feb 23. PMID: 36822815
A class of anti-inflammatory lipids decrease with aging in the central nervous system.

Tan D, Konduri S, Erikci Ertunc M, Zhang P, Wang J, Chang T, Pinto AFM, Rocha A, Donaldson CJ, Vaughan JM, Ludwig RG, Willey E, Iyer M, Gray PC, Maher P, Allen NJ, Zuchero JB, Dillin A, Mori MA, Kohama SG, Siegel D, Saghatelian A. Nat Chem Biol. 2023 Feb;19(2):187-197. doi: 10.1038/s41589-022-01165-6. Epub 2022 Oct 20. PMID: 36266352

CNS myelination requires VAMP2/3-mediated membrane expansion in oligodendrocytes.
Lam M, Takeo K, Almeida RG, Cooper MH, Wu K, Iyer M, Kantarci H, Zuchero JB. Nat Commun. 2022 Sep 23;13(1):5583. doi: 10.1038/s41467-022-33200-4. PMID: 36151203

Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17.
Iram T, Kern F, Kaur A, Myneni S, Morningstar AR, Shin H, Garcia MA, Yerra L, Palovics R, Yang AC, Hahn O, Lu N, Shuken SR, Haney MS, Lehallier B, Iyer M, Luo J, Zetterberg H, Keller A, Zuchero JB, Wyss-Coray T. Nature. 2022 May;605(7910):509-515. doi: 10.1038/s41586-022-04722-0. Epub 2022 May 11. PMID: 35545674

Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM.
Lanz TV, Brewer RC, Ho PP, Moon JS, Jude KM, Fernandez D, Fernandes RA, Gomez AM, Nadj GS, Bartley CM, Schubert RD, Hawes IA, Vazquez SE, Iyer M, Zuchero JB, Teegen B, Dunn JE, Lock CB, Kipp LB, Cotham VC, Ueberheide BM, Aftab BT, Anderson MS, DeRisi JL, Wilson MR, Bashford-Rogers RJM, Platten M, Garcia KC, Steinman L, Robinson WH. Nature. 2022 Mar;603(7900):321-327. doi: 10.1038/s41586-022-04432-7. Epub 2022 Jan 24. PMID: 35073561

Modeling myelin: A toolkit for exploring myelin's mysteries in vitro.
Cooper MH, Zuchero JB. Dev Cell. 2021 May 3;56(9):1215-1217. doi: 10.1016/j.devcel.2021.04.015. PMID: 33945781

Label-free optical detection of bioelectric potentials using electrochromic thin films.
Alfonso FS, Zhou Y, Liu E, McGuire AF, Yang Y, Kantarci H, Li D, Copenhaver E, Zuchero JB, Müller H, Cui B. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):17260-17268. doi: 10.1073/pnas.2002352117. Epub 2020 Jul 6. PMID: 3263200

How Support of Early Career Researchers Can Reset Science in the Post-COVID19 World.
Gibson EM, Bennett FC, Gillespie SM, Güler AD, Gutmann DH, Halpern CH, Kucenas SC, Kushida CA, Lemieux M, Liddelow S, Macauley SL, Li Q, Quinn MA, Roberts LW, Saligrama N, Taylor KR, Venkatesh HS, Yalçın B, Zuchero JB. Cell. 2020 Jun 25;181(7):1445-1449. doi: 10.1016/j.cell.2020.05.045. PMID: 32533917

Anchors Away: Glia-Neuron Adhesion Regulates Myelin Targeting and Growth.
Garcia MA, Zuchero JB. Developmental Cell. 2019 51:659-661. doi: 10.1016/j.devcel.2019.11.018. PMID: 31951538

A Tribute to Ben Barres: Remembrances from Barres Lab Members
Eroglu C, Emery B, Stevens B, Daneman R, Allen NJ, Ullian EM, Zhang Y, Zuchero JB, Foo LC, Agalliu D, Bennett M. Developmental Cell. 2018 44:4415-419.

Schwann cells use TAM receptor-mediated phagocytosis in addition to autophagy to clear myelin in a mouse model of nerve injury.
Brosius Lutz A, Chung WS, Sloan SA, Carson GA, Zhou L, Lovelett E, Posada S, Zuchero JB, Barres BA. Proc Natl Acad Sci USA. 2017 Sep 19;114(38):E8072-E8080.
PMID: 28874532

DeActs: genetically encoded tools for perturbing the actin cytoskeleton in single cells.
Harterink M, da Silva ME, Will L, Turan J, Ibrahim A, Lang AE, van Battum EY, Pasterkamp RJ, Kapitein LC, Kudryashov D, Barres BA, Hoogenraad CC, Zuchero JB. Nature Methods. 2017 May;14(5):479-482.
PMID: 28394337      DeActs plasmids available at addgene: LINK

Glia in mammalian development and disease.
Zuchero JB, Barres BA. Development. 2015 Nov 15;142(22):3805-9.
PMID: 26577203.

CNS myelin wrapping is driven by actin disassembly.
Zuchero JB, Fu MM, Sloan SA, Ibrahim A, Olson A, Zaremba A, Dugas JC, Wienbar S, Caprariello AV, Kantor C, Leonoudakis D, Lariosa-Willingham K, Kronenberg G, Gertz K, Soderling SH, Miller RH, Barres BA. Developmental Cell. 2015 Jul 27;34(2):152-67.
PMID: 26166300

Type IV collagen is an activating ligand for the adhesion G protein-coupled receptor GPR126.
Paavola KJ, Sidik H, Zuchero JB, Eckart M, Talbot WS. Science Signaling. 2014 Aug 12;7(338):ra76.
PMID: 25118328.

Purification and culture of dorsal root ganglion neurons.
Zuchero JB. Cold Spring Harb Protoc. 2014 Aug 1;2014(8):813-4.
PMID: 25086024.

Purification of dorsal root ganglion neurons from rat by immunopanning.
Zuchero JB. Cold Spring Harb Protoc. 2014 Aug 1;2014(8):826-38.
PMID: 25086011.

Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain.
Gibson EM, Purger D, Mount CW, Goldstein AK, Lin GL, Wood LS, Inema I, Miller SE, Bieri G, Zuchero JB, Barres BA, Woo PJ, Vogel H, Monje M. Science. 2014 May 2;344(6183):1252304.
PMID: 24727982.

Cytoplasmic actin: purification and single molecule assembly assays.
Hansen SD, Zuchero JB, Mullins RD. Methods Mol Biol. 2013;1046:145-70.
PMID: 23868587.

Intrinsic and extrinsic control of oligodendrocyte development.
Zuchero JB, Barres BA. Curr Opin Neurobiol. 2013 Dec;23(6):914-20.
PMID: 23831087.

Generation of oligodendroglial cells by direct lineage conversion.
Yang N, Zuchero JB, Ahlenius H, Marro S, Ng YH, Vierbuchen T, Hawkins JS, Geissler R, Barres BA, Wernig M. Nature Biotechnology. 2013 May;31(5):434-9.
PMID: 23584610.

Actin binding to WH2 domains regulates nuclear import of the multifunctional actin regulator JMY.
Zuchero JB, Belin B, Mullins RD. Mol Biol Cell. 2012 Mar;23(5):853-63.
PMID: 22262458.

Between the sheets: a molecular sieve makes myelin membranes.
Zuchero JB, Barres BA. Developmental Cell. 2011 Sep 13;21(3):385-6.
PMID: 21920305

Hts/Adducin controls synaptic elaboration and elimination.
Pielage J, Bulat V, Zuchero JB, Fetter RD, Davis GW. Neuron. 2011 Mar 24;69(6):1114-31.
PMID: 21435557.

p53-cofactor JMY is a multifunctional actin nucleation factor.
Zuchero JB, Coutts AS, Quinlan ME, Thangue NB, Mullins RD. Nature Cell Biology. 2009 Apr;11(4):451-9.
PMID: 19287377.

In vitro actin assembly assays and purification from Acanthamoeba.
Zuchero JB. Methods Mol Biol. 2007;370:213-26.
PMID: 17416997.